Recent News 41 : A New Lab Working on Phage Therapy in Lausanne, Switzerland

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Bacteriophage and Phage Therapy Laboratory

Photo taken from : https://www.chuv.ch/fr/crisp/therapies-innovantes-biologiques-et-cellulaires/laboratoire-des-bacteriophages-et-de-phagotherapie

Antibiotics are essential drugs for the treatment of infectious diseases, but the prevalence of multidrug-resistant (MDR) bacteria continues to call their effectiveness into question. Given the limited number of new drugs currently in clinical development, it is essential to evaluate alternative non-antibiotic treatments. Bacteriophages (phages) are ubiquitous natural bacterial predators that specifically infect and kill bacterial cells during their life cycle. Bacteriophages also produce endolysins (lysins) as part of their lytic cycle to degrade the peptidoglycan layer of infected bacteria to release the phage progeny. Due to the rapid lethal action of purified recombinant forms of these enzymes when added extrinsically to Gram-positive bacteria, they are currently being actively exploited as novel anti-infectives, sometimes referred to as enzybiotics.

In the Bacteriophage and Phage Therapy Laboratory, we develop new therapeutic phages and phage-lysins using a rational approach.

The Team

Dr Grégory Resch

Dr Grégory Resch

MER
Responsable du Laboratoire des bactériophages
Archana Loganathan

Dre Archana Loganathan

Post-doctorante
Nicolas Villa

Dr Nicolas Villa

Post-doctorant
Raphaël Baudin

Raphaël Baudin

Assistant doctorant
Hugues De Villiers de la Noue

Hugues De Villiers de la Noue

Assistant doctorant
Anthony Vocat

Anthony Vocat

Assistant doctorant
Nathalie Bonvin

Nathalie Bonvin

Technicienne de laboratoire
Laboratoire des bactériophages
Aurélie Marchet

Aurélie Marchet

Technicienne de laboratoire
Sabrina Pereira Pipa

Sabrina Pereira Pipa

Laborantine
Laboratoire des bactériophages
Norah Alibrando

Norah Alibrando

Apprentie laborantine en biologie




Contact

Dr Grégory Resch
Responsable du laboratoire
Avenue de Beaumont
1011 Lausanne
Contact Form



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